Fig. 5
From: H3K4 methylation regulates development, DNA repair, and virulence in Mucorales
set1 is essential for M. lusitanicus virulence. Virulence of M. lusitanicus strains in G. mellonella model host inoculated with 106 spores of the WT strain (MU636) and set1 mutants through the last pro-leg into the hemocoel. Percentage survival values were plotted for 6 days. Untouched larvae and larvae injected with IPS were used as control. Survival curves were statistically analyzed by log-rank (Mantel-Cox) test, utilizing GraphPad Prism 8.0.2 software. The difference in survival between set1 mutants and wild-type strain was statistically significant (P values ≤ 0.05)