Table 1 Fungal enzymes involved in fucose metabolism
From: Fucose as a nutrient ligand for Dikarya and a building block of early diverging lineages
EC | Recommended Name | Pfam id | Pfam name | Function | Uniprot reference |
|---|---|---|---|---|---|
1.1.1.271 | GDP-L-fucose synthase | PF01370 | Epimerase | GDP-L-fucose synthesis (de novo) | Q13630 |
4.2.1.47 | GDP-mannose 4,6-dehydratase | PF16363 | GDP_Man_Dehyd | GDP-L-fucose synthesis (de novo) | O60547 |
2.4.1.152 2.4.1.214 2.4.1.65 | L-fucosyltransferases | PF00852, PF17039 | Glyco_transf_10, Glyco_tran_10_N | Protein/lipids modification | P22083 Q11130 P21217 |
2.4.1.- | Fucosyltransferase | PF03254 | XG_FTase | Polysaccharide modification | Q9SWH5 |
2.4.1.221 | peptide-O- fucosyltransferase | PF10250 | O-FucT | Protein modification | Q9Y2G5 |
2.4.1.68 | glycoprotein 6-alpha- L-fucosyltransferase | PF14604, PF19745 | SH3_9, FUT8_N_cat | Protein modification | Q9BYC5 |
2.4.1.222 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | PF02434 | Fringe | Fucosylated protein modification | Q8NES3 |
2.7.1.52 | fucokinase | PF07959,PF08544, PF00288 | Fucokinase, GHMP_kinases_C, GHMP_kinases_N | GDP-L-fucose synthesis (salvage) | Q8N0W3 |
2.7.7.30 | fucose-1-phosphate guanylyltransferase | PF07959 | Fucokinase | GDP-L-fucose synthesis (salvage), fucose recycling | O14772 |
3.2.1.51 | alpha-L-fucosidase | PF01120, PF16757 | Alpha_L_fucos, Fucosidase_C | Fucose degradation | Q9BTY2 |
3.2.1.63 | 1,2-alpha-L-fucosidase | PF14498 | Glyco_hyd_65N_2 | Fucose polysaccharide degradation | Q6JV24 |
4.2.1.68 | L-fuconate dehydratase | PF13378, PF02746 | MR_MLE_C, MR_MLE_N | Fucose degradation | Q8P3K2 |
5.1.3.29 | L-fucose mutarotase | PF05025 | RbsD_FucU | Fucose degradation | A2VDF0 |