Skip to main content

Advertisement

Table 2 MSDIN peptide sequences from Amanita subjunquillea (As).

From: The MSDIN family in amanitin-producing mushrooms and evolution of the prolyl oligopeptidase genes

No. Leader peptide Core Peptide Recognition Sequence Scaffold Coding and Notes
1 MSDINATCLP IWGIGCNP IWGIGCNP 1 α-amanitin
2 MSDINATRLP IWGIGCNP IWGIGCNP 1 β-amanitin
3 MSDINATRLP IWGIGCDP CIGDDVTALLTRGEALC 1 β-amanitin
4 MSDINATRLP AWLVDCP CVGDDVTALLTRGEALC 1 phallacidin
5 MSDINTARLP HFASFIPP CIGDDVTALLTRGEALC 1  
6 MSDINTARLP TFLPPLFVPP CVSDDVTALLTRGEALC 1  
7 MSDINATRLP AWLATCP CAGDDVTALLTRGEALC 2 phalloidin
8 MSDINATRLP LNILPFMLPP CVGDDVTALLTRGEALC 54  
9 MSDMNATRLP LIQRPFAP CVSDDVTALLTRGEALC 41  
10 MSDMNATRLP LIQRPYAP CVSDDVTALLTRGEALC 10  
11 MFDINITRLP IFWFIYFP CVGDDVTALLTRGEALC 8  
12 MSDINTARLP IGRPESIP CVGDDVTALLTRGEALC 13  
13 MSDINTARLP LRLPPFMIPP CVGDDVTALLTRGEALC 13  
14 MSDMNVARLP ISDPTAYP CVGGDVTALLTRGEALC 13 2 copies, in Apa
15 MSDINTVCLP LQKPWSRP CVGDDVTALLTRGEALC 13  
16 MSDVNATRLP FNFFRFPYP CIGDDVTALLTRGEALC 38  
17 MSDINATRLP SSVLPRP CVGDDVTALLTRGEALC 20  
18 MSDMNVARLP ISDPTAYP CVGGDVTALLTRGEALC 22 2 copies, in Apa
  1. Core peptides (correspond to cyclic peptide toxins) are in bold.
  2. The conserved MSDIN (except for the ones with variations) is underlined.
  3. No. 14 and 18 have two copies and are also in A. pallidorosea.