The MSDIN family in amanitin-producing mushrooms and evolution of the prolyl oligopeptidase genes

IMA Fungus

Table 3 MSDIN peptide sequences from Amanita pallidorosea (Apa).

Name	Leader peptide	Core Peptide	Recognition Sequence	Scaffold	Coding
1	MSDINATRLP	IWGIGCNP	CVGDDVTALLTRGEALC	52	α-amanitin, 2 copies
2	MSDINATRLP	IWGIGCNP	CVGDDVTALLTRGEALC	52	α-amanitin, 2 copies
3	MSDINATRLP	IWGIGCDP	CVGDDVTALLTRGEALC	52	β-amanitin
4	MSDVNATRLP	MAFPEFLA	CVGDDVTALLTRGEALC	52
5	MSDINATRLP	AWLMTCP	CVGDDVTALLTRGEALC	7
6	MSDVNATRLP	AWLVDCP	CVGDDVTALLTRGEALC	62	phallacidin
7	MSDINASRLP	FFPEVGFFP	CVGDDVTALLTRGEALC	16
8	MSDINAIRAP	LPIFSLNP	CVGDDVTALLTRGEALC	16
9	MSDINATRLP	NWHAGPTRPP	CVADDVTALLTRGEALC	16
10	MSDINAARLP	NLFVWIPP	CISDDVTALLTRGEALC	16
11	MSDINASRLP	AWLATCP	CAGDDVTALLTRGEALC	16	phalloidin
12	MADINASRLP	LNILPFHLPP	CVSDDVTALLTRGEALC	16
13	MSDINATRLP	LGRPESLP	CVGDDVTALLTRGEALC	3
14	MSDINATRLP	HPFPLGLQP	CAGDDVTALLTRGEALC	73	2 copies
15	MSDINATRLP	HPFPLGLQP	CAGDDVTALLTRGEALC	101	2 copies
16	MSDMNVVRLP	ISDPTAYP	CVGDDVTALLTRGEALC	102	2 copies, in As
17	MSDINVIRLP	*IFFIYFP**	CVGDNVTALLTRGEALC	60
18	MSDINTARLP	MHILAPPP	CVSDDVTALLTRGEALC	10
19	MSDMNVVRLP	ISDPTAYP	CVGDDVTALLTRGEALC	64	2 copies, in As
20	MSDTNATRLP	SIFIVYPP	CVSDDVTALLTRGEALC	86
21	MSDINAARLP	LVYMILFP	SVGDDVTALLTRGEALC	111
22	MSETNAARLP	TIHLFSAP	SVGDDVTALLTRGEALC	111
23	MSDINTARLP	EFIVFGIFP	CVGDDVTALLTRGEALC	78
24	MSDINTTRLP	YFFNDHPP	CASDDVTALLTRGEALC	78
25	MSDLNATRLP	FNLFRFPYP	CIGDDVTALLTRGEALC	9
26	MSDINTARLP	VFFMPPFIPP	CVSDDVTALLTRGEALC	1
27	MSNINTARLP	FLVPSFPP	CVSDDVTALLTRGEALC	1
28	MYDINTTRLP	HFFNLTPP	CVRDDVTALLTRGEALC	39
29	MSDINTARLP	FVIIPPFIFP	CVSDDVTALLTRGEALC	12

ISSN: 2210-6359