Skip to main content

Advertisement

Table 3 MSDIN peptide sequences from Amanita pallidorosea (Apa).

From: The MSDIN family in amanitin-producing mushrooms and evolution of the prolyl oligopeptidase genes

Name Leader peptide Core Peptide Recognition Sequence Scaffold Coding
1 MSDINATRLP IWGIGCNP CVGDDVTALLTRGEALC 52 α-amanitin, 2 copies
2 MSDINATRLP IWGIGCNP CVGDDVTALLTRGEALC 52 α-amanitin, 2 copies
3 MSDINATRLP IWGIGCDP CVGDDVTALLTRGEALC 52 β-amanitin
4 MSDVNATRLP MAFPEFLA CVGDDVTALLTRGEALC 52  
5 MSDINATRLP AWLMTCP CVGDDVTALLTRGEALC 7  
6 MSDVNATRLP AWLVDCP CVGDDVTALLTRGEALC 62 phallacidin
7 MSDINASRLP FFPEVGFFP CVGDDVTALLTRGEALC 16  
8 MSDINAIRAP LPIFSLNP CVGDDVTALLTRGEALC 16  
9 MSDINATRLP NWHAGPTRPP CVADDVTALLTRGEALC 16  
10 MSDINAARLP NLFVWIPP CISDDVTALLTRGEALC 16  
11 MSDINASRLP AWLATCP CAGDDVTALLTRGEALC 16 phalloidin
12 MADINASRLP LNILPFHLPP CVSDDVTALLTRGEALC 16  
13 MSDINATRLP LGRPESLP CVGDDVTALLTRGEALC 3  
14 MSDINATRLP HPFPLGLQP CAGDDVTALLTRGEALC 73 2 copies
15 MSDINATRLP HPFPLGLQP CAGDDVTALLTRGEALC 101 2 copies
16 MSDMNVVRLP ISDPTAYP CVGDDVTALLTRGEALC 102 2 copies, in As
17 MSDINVIRLP IF*FIYFP CVGDNVTALLTRGEALC 60  
18 MSDINTARLP MHILAPPP CVSDDVTALLTRGEALC 10  
19 MSDMNVVRLP ISDPTAYP CVGDDVTALLTRGEALC 64 2 copies, in As
20 MSDTNATRLP SIFIVYPP CVSDDVTALLTRGEALC 86  
21 MSDINAARLP LVYMILFP SVGDDVTALLTRGEALC 111  
22 MSETNAARLP TIHLFSAP SVGDDVTALLTRGEALC 111  
23 MSDINTARLP EFIVFGIFP CVGDDVTALLTRGEALC 78  
24 MSDINTTRLP YFFNDHPP CASDDVTALLTRGEALC 78  
25 MSDLNATRLP FNLFRFPYP CIGDDVTALLTRGEALC 9  
26 MSDINTARLP VFFMPPFIPP CVSDDVTALLTRGEALC 1  
27 MSNINTARLP FLVPSFPP CVSDDVTALLTRGEALC 1  
28 MYDINTTRLP HFFNLTPP CVRDDVTALLTRGEALC 39  
29 MSDINTARLP FVIIPPFIFP CVSDDVTALLTRGEALC 12  
  1. Core peptides (correspond to cyclic peptide toxins) are in bold.
  2. The conserved MSDIN (except for the ones with variations) is underlined.
  3. No. 14 and 15 have two copies.
  4. No. 16 and 19 have two copies and are also in A. subjunquillea.
  5. *indicates a stop codon exists in the sequence.