Comparison secondary metabolism backbone genes and related genes in Botryosphaeria dothidea and B. kuwatsukai to other 12 fungi species involved in different lifestyles. (A) For each secondary metabolism backbone gene family and predicted total gene numbers are shown in cells. Over-represented (+3 to 0) and under-represented (0 to −3) numbers are depicted as Z-scores for each line in heatmap. (B) The number of MFS_1 (PF07690) family, ABC_tran (PF00005) family and CYP family were compared between B. dothidea or B. kuwatsukai and all the genomes. (B) Comparative analyses of orthologous of secondary metabolism backbone genes in B. dothidea PG45 and B. kuwatsukai PG2. Orthologs were determined by BDBHs.